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Prunus africana (Pygeum africanum)

africananspPrunus africana, or red stinkwood, is a little known plant species. It is also rarely used in medicine – despite its proven properties that facilitate treatment of prostatic hypertrophy.

What does Prunus africana look like and where does it come from?

The Latin name of the plant already suggests its origin. It is a tree five to forty metres tall growing wild in the montane tropical forests of Africa, as well as in South Africa. It has been found that aside from the mountain climate, Prunus africana also favours areas with volcanic residues (ash and dust).

Active ingredient contents in Prunus africana

The extract of the Prunus africana bark contains phytosterols, tannins, triterpene esters, lipid acids and phenolic acids.

Phytosterols are the most important substances due to their therapeutic effects. When explaining what phytosterols are, they can be compared to hormones, or even considered as hormone substitutes/equivalents. Phytosterols "pretend" to be natural hormones by their action. In the therapy of prostatic hypertrophy, phytosterols are used to "stand in for" the hormone DHT (a derivative of testosterone). When phytosterols enter the body of a male, they are metabolised just like DHT would be. Note that the original derivative of testosterone contributes to further overgrowth of the prostate, while the metabolism of phytosterols result in compounds that do not destructively affect the condition of the gland.

The lack of adverse effect on the prostate is not the only advantage of administering extracts from Prunus africana. Phytosterols from the bark of Prunus africana also regenerate the prostatic epithelial cells. At the same time they reduce the tone of muscles around the urethra and the ureter, the effect of which is the free discharge of urine. In addition the anti-inflammatory properties phytosterols should be noted, which can also alleviate prostatic hypertrophy, since inflammation usually accompanies the disorder.

Therapeutic indications for the Prunus africana extract

The primary indication, which is mild prostatic hypertrophy, has already been discussed. The extract of Prunus africana bark is used to aid in the treatment of polyuria, or nocturnal enuresis (which is uncontrolled urination during sleep). The extract of Prunus africana is used in inflammation of the urinary system.

An interesting indication for Prunus africana are dermal disorders such as psoriasis, adult acne (rosacea) or androgenic acne (which results from hormonal variations).

Prunus africana is also a choice in anti-rheumatoid therapies and treatment of autoimmunological diseases (that result from hyperactivity of the immune system).

Poldanen, a drug for the prostate

The efficacy of phytosterols in the treatment of mild prostatic overgrowth is beyond any doubt. It is also known that phytosterols should be extracted from the bark extract of Prunus africana. The preparation Poldanen meets both requirements. It is a pharmaceutical drug for patients with diagnosed mild prostatic hypertrophy to effectively inhibit the progress of the disorder and to neutralise its unpleasant symptoms, such as the need to urinate frequently, the sensation of incomplete emptying of the bladder, as well as the pain and burning during urination.

Administration of Poldanen

Poldanen is taken for a minimum of one month. The regular recommended dose is four tablets a day in the regime of two tablets two times a day (best taken during meals). Treatment with Poldanen can be extended if necessary.

Products containing Prunus africana

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